Stage I

Tumors that are 0-2.0mm without ulceration or 0-1.0mm with ulceration. 

Surgical excision is highly effective (90% cure rate for lesions <1mm).

Stage II

Tumors that are 1.01mm or greater and are ulcerated or 2.01 mm or more and are non-ulcerated.

Stage III-Regional Disease

The primary tumor has satellite or in-transit metastasis or has spread to regional lymph nodes. Treatment includes lymph node resection and in some cases biologic therapy.

Stage IV-Distant Metastasis

Tumor has spread beyond the lymph nodes, usually to lung (70-80%), liver (54-77%), or brain (36-54%). Treatment includes biologic therapy using interleukin-2 and/or chemotherapy or participation in a clinical trial.

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